Proposal of situational‐meaning agnosia/endogenous‐reaction hypothesis for schizophrenia
نویسندگان
چکیده
منابع مشابه
[Glutamatergic hypothesis of schizophrenia].
Schizophrenia is a devastating psychiatric disorder whose pathophysiology has not been fully clarified yet. Although dopamine dysfunction in schizophrenia is unequivocal, there are many evidences suggesting the involvement of the glutamatergic system. This paper briefly describes some basic knowledge regarding the functioning of the glutamatergic receptors with emphasis on the N-methyl-D-aspart...
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The neurodevelopmental hypothesis of schizophrenia provided a valuable framework that allowed a condition that usually presents with frank disorder in adolescence or early adulthood to be understood at least in part as a consequence of events occurring early in development. However, the implications of the neurodevelopmental hypothesis for nosological conceptions of the disorder can only now be...
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The predominant biological hypothesis for a neurochemical defect in schizophrenia is currently the socalled "dopamine (DA) hypothesis." In its simplest form, this hypothesis states that schizophrenia may be related to a relative excess of DA-dependent neuronal activity. It is derived from pharmacologic evidence that drugs that decrease DA activity (e.g., the phenothiazines) may be antipsychotic...
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to schizophrenia is well established by the higher preva-Columbia College of Physicians and Surgeons lence of schizophrenia in relatives of patients with New York, New York 10032 schizophrenia (Kendler and Diehl, 1993). Since the con-2 Instituto Cajal cordance rate in monozygotic twins is about 50%, non-Consejo Superior de Investigaciones Científicas genetic risk factors also play a role in the...
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ژورنال
عنوان ژورنال: Psychiatry and Clinical Neurosciences
سال: 2019
ISSN: 1323-1316,1440-1819
DOI: 10.1111/pcn.12908